Top 10 of emerging technologies
By the World Economic Forum’s Meta-Council on Emerging Technologies
Pharma involved in OoC
Emulate, Inc. announced that it formed a research collaboration with Janssen Biotech, Inc.
hDMT consortium
Precompetitive, non-profit technological R&D institute - Valorizes Organ-on-Chip models - Promotes open knowledge exchange and collaborations in OoC
Pharmas fund OoC in Europe
OoC technology combined with high throughput screening of primary human cells. - OoC predict renal toxicity during pre-clinical development.
First US OoC Start-up
Emulate: spin-off from the Wyss Institute - OoC put on the market - Drug testing applications
US Human on a chip initiative
FDA: partner in this 2012 Tissue Chip program - NIH and DARPA fund research grant in OoC
Establishment of European OoC Companies
OoC: a potential to transform the drug discovery industry Co-culture of two cell types in a common medium Multi-organ chip platform
Birth of Organ-on-Chip
Wyss Institute Airway-on-a-chip device Read "Huh D. et al, 2010"
Before 2010 Organ-on-Chip
Microphysiological systems (MPS) Improved long-term cellular viability with microfluidics See also Pioneers in the microfluidic cell culture field: Groups of Mike Shuler, Linda Griffith, Roger Kamm, Dave Beebe, Eric LeClerc/Teruo Fujii, Danny van Noort… Read "Lee P.J. et al, 2007"