Bone-on-Chip Analysis Platform for In Vitro Drug Performance Evaluation. BONAFIDE
• BEONCHIP S.L.
• OCELLO B.V.
• Academisch Centrum Tandheelkunde Amsterdam
Simulate bone growth, resorption and remodeling for medium/high throughput evaluation of drugs
BONAFIDE will develop, validate and deliver an in vitro human bone-on-chip platform that will simulate bone growth, resorption and remodeling for medium/high throughput evaluation of drugs (e.g. anti-osteoporosis, nutrients, and biomaterials (e.g. bone cements). The BONAFIDE platform can be directly implemented in the preclinical workflow of companies and consist of a microfluidic chip containing a bone-mimetic matrix and standard operating procedures for human bone culture.