Bone-on-Chip Analysis Platform for In Vitro Drug Performance Evaluation. BONAFIDE

Partners/Institution :

• BEONCHIP S.L.

• OCELLO B.V.

• Academisch Centrum Tandheelkunde Amsterdam

Key application :

Simulate bone growth, resorption and remodeling for medium/high throughput evaluation of drugs

Description :

BONAFIDE will develop, validate and deliver an in vitro human bone-on-chip platform that will simulate bone growth, resorption and remodeling for medium/high throughput evaluation of drugs (e.g. anti-osteoporosis, nutrients, and biomaterials (e.g. bone cements). The BONAFIDE platform can be directly implemented in the preclinical workflow of companies and consist of a microfluidic chip containing a bone-mimetic matrix and standard operating procedures for human bone culture.

MORE PROJECT’S INFORMATION

Tissue/organ model: Bone

Application: Simulate bone growth, resorption and remodeling for medium/high throughput evaluation of drugs

Project timeline: Jan 2017 – Dec 2019

Countries: Spain, The Netherlands

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