January 12, 2024 EUROoCS

Digital lectures: Alexander S. Mosig (25 January 2024)


On January 25th, the 2024 EUROoCS digital lecture series will kick off with a lecture by Dr. Alexander S. Mosig about ‘Organ-on-chip to dissect host-pathogen interaction’.
Dr. Mosig is affiliated with both the Institute of Biochemistry II, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany and the Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, Jena, Germany.

Alexander Mosig studied Biochemistry and Molecular Biology and obtained his PhD in Cell Biology from the Friedrich Schiller University Jena. He is the independent research group leader of the INSPIRE lab at the Center for Sepsis Control and Care of the Jena University Hospital, focusing on studies on the orchestration of the human immune response by the microbiota in organ-specific environments. He is interested in mechanisms of host-pathogen interaction and its regulation by microbiota-associated metabolites in the context of dysbiosis and acute and chronic inflammatory diseases. An important topic of his work is developing and applying novel microphysiological systems to study these processes in vitro.

Dr. Mosig studies host-microbiota interactions and the human cellular immune response to infections and inflammations, utilizing innovative organ-on-chip systems. This work includes an exploration of the plasticity of myeloid cells and regulating tissue-specific immunological niches during disease progression. A significant aspect of his research involves developing microphysiological model systems for replicating specific human organ functions in vitro, focusing on immune responses to various pathologies, including viral and bacterial infections and inflammation-related disorders. The team led by Dr. Mosig employs a multidisciplinary approach, integrating cell biology, biochemistry, microbiology, and bioengineering.

Please register for the digital meeting here

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