European Organ-on-Chip Society open for active membership

Press release: European Organ-on-Chip Society open for active membership

The founding phase is complete: the European Organ-on-Chip Society (EUROoCS) is now welcoming members to join. The annual conference, held this year in Graz (Austria), saw launch of the community website and the start of its availability as an information resource. “We invite scientists, engineers, as well as regulators and patient representatives interested in these new laboratory models to become active members of the society and contribute to efforts of the Organ-on-Chip community in promoting recognition and implementation of  this exciting research field,” says Christine Mummery, chair of EUROoCS and professor of Developmental Biology at Leiden University Medical Center, the Netherlands

 

3 July 2019 – Organ-on-Chip (OoC) systems are among the latest emerging technologies for healthcare research. It is believed they will accelerate drug discovery, advance drug efficacy and toxicology testing and open new opportunities for personalized medicine. “Organ-on-Chip systems can reduce and perhaps eventually replace animal experiments and provide predictive human data before expensive and lengthy clinical trials actually start,” vice-chair Peter Loskill says. The biophysicist heads the Organ-on-Chip research group at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Germany.

 

Building a community network

Although the potential of OoC technology is high, it is also very complex. Organ-on-Chip systems hold human cells, tissues or mini-organs in mimics of their own microenvironment while they perform real-life tissue functions. This requires considerable interdisciplinary collaboration – especially between biology, engineering and physics, disciplines only recently in close contact. “We established the European Organ-on-Chip Society to bring together all relevant stakeholders and build an expert network. In this way we provide a platform for exchange of scientific knowledge across disciplines and collaboration opportunities,” says Janny van den Eijnden-van Raaij, secretary of EUROoCS and managing director of the Dutch institute hDMT. “Involving all stakeholders at an early stage is key to success and rapid development of Organ-on-Chip technology.”

Many scientists with interest registered earlier are now invited to contribute and participate actively in the OoC community.

 

Making the difference

High on EUROoCs agenda is identifying “showcases” that demonstrate the potential of OoC-technology and how it can make a difference in discovery of safe and effective drugs. EUROoCs promotes the development of reliable and robust model systems, open technology platforms, standardization and discussion of ethical aspects. “We have to work on approaches for the integration of physical or chemical sensors, and ensure that the test systems deliver reproducible and comparable results and can also be standardized from a regulatory point of view,” says board member Albert van den Berg, professor of sensor systems for biomedical and environmental applications at the University of Twente, the Netherlands. “Furthermore, we need to think about the manufacturability and integration in the user’s workflow at an early stage if we want to have real impact.”

  

Membership benefits

The society is open to individual researchers and students worldwide and to individual representatives of industry and regulatory agencies. Anyone with a real interest in Organ-on-Chip technology is welcome to join and share ideas and knowledge. Student members enjoy a 50% reduction on the € 40,-  annual membership fee.

Member benefits include exclusive access to the digital platform (with forum, research projects and expert profiles), discounted registration for the annual conference and up-to-date information on advances and activities in the OoC field.

Stay tuned and join the Organ-on-Chip Society: https://www.euroocs.eu/become-a-member/

Become part of a growing network and help move this emerging technology forward.

More information

www.euroocs.eu

 Contact

Dr. Janny van den Eijnden – van Raaij
Board EUROoCS
Managing Director hDMT
T: +31 6 1299 8074
E: j.vandeneijnden@hdmt.technology

 

About Organ-on-Chip systems

An Organ-on-Chip is a fit-for-purpose microfluidic device, containing living engineered organ substructures in a controlled microenvironment, that recapitulates one or more aspects of the organ’s dynamics, functionality and (patho)physiological response in vivo under real-time monitoring.

Organ-on-chip models are expected to result in a paradigm shift for healthcare, leading to new ways to elucidate disease mechanisms in humans, identify effective drugs and improve health by prevention and personalized cure of many diseases.

About EUROoCS

The European Organ-on-Chip Society (EUROoCS) is an independent, not-for-profit organization established to encourage and develop Organ-on-Chip research, and to provide opportunities to share and advance knowledge and expertise in the field towards better health for all. EUROoCS was launched November 2018 during the 3rd International Organ-on-Chip Symposium at the University of Technology in Eindhoven, the Netherlands.

EUROoCS is an outcome of the Horizon 2020 project ORCHID (Organ-on-Chip in Development) carried out by a European consortium of seven partner organizations.

www.euroocs.eu

About ORCHID

The Horzion 2020 ORCHID project (Organ-on-Chip development) is an EU initiative, coordinated by Leiden University Medical Center and the Dutch Organ-on-Chip consortium hDMT in the Netherlands. The main goal of ORCHID is to create a roadmap for Organ-on-Chip technology and to build a network of all relevant stakeholders in this promising innovative field. In the two years ORCHID project that started on 1 October 2017 in total seven leading European research institutions from five different European countries are involved.

H2020-ORCHID.eu

  About hDMT

hDMT (Institute for human Organ and Disease Model technologies) is a pre-competitive, non-profit, technological research institute, in which renowned scientists from 15 Dutch organizations (academic research centers, research institutes, University Medical Centers, and biotech companies) work together. In this consortium hDMT researchers share and integrate their knowledge, expertise and research facilities in technology, biology, physics, chemistry, pharmacology and medicine to develop Organs-on-Chips largely using human stem cells. hDMT aims to disseminate Organ-on-Chip models and research data via open access publication and valorization.

www.hdmt.technology

Impression of the ORCHID Strategy workshop

Following up on the ORCHID Vision workshop, the ORCHID Strategy workshop was held in Leiden, the Netherlands on 17 January 2019. 32 experts from academia, innovation hubs, pharmaceutical and cosmetic industry, patient organizations, ethics school, biotech companies and regulatory agencies attended the workshop. They represented developers, end users and regulators in the Organ-on-Chip (OoC) field in Europe. The workshop was organized by Janny van den Eijnden-van Raaij from hDMT (work package leader Roadmap) and chaired by Christine Mummery from LUMC (coordinator).

The aim of this workshop was to define the concrete goals and milestones of the OoC roadmap, and the strategy to reach them. During two brainstorm sessions, expert groups focused on four specific application domains: personalized medicine, drug efficacy, drug toxicity and disease mechanisms. The groups addressed domain-specific issues from the perspective of both developers and of end users and regulators. The specific building blocks of the OoC roadmap were identified and the general aspects of the roadmap were also discussed, such as ethical concerns, training of the next generation OoC researchers, dissemination and communication.

It was again a very useful meeting, that positively contributed to the strengthening of the network and building of the OoC ecosystem in Europe. The report of the ORCHID Strategy workshop is currently in preparation and will be publicly available in short time.

 

Registration is open: EUROoC 2019, 2-3 July 2019 in Graz

This year the annual EUROoCS Organ-on-Chip conference will be organized in Graz, in Austria, on 2 and 3 July 2019. It will provide many opportunities for scientific discussion and interaction, and bring together young scientists with top experts in the field.

The EUROoC conference series aims to gather the research leaders in the emerging field organs-on-chip (OoC) with a special focus on young and upcoming scientists. The extremely interdisciplinary field of OoC research is rapidly growing while new and innovative systems are constantly being developed. However, a variety of engineering challenges are remaining, which the OoC field has to address as a whole to enable a sustainable growth of this breakthrough technology.

The EUROoC 2019 is a scientific meeting focused on the challenges in the process of designing, fabricating, and implementing microphysiological cell culture systems addressing topics such as microfabrication of 3D matrices, integration of miniaturised sensors, microfluidic interfacing, cellular engineering, parallelization and automation.

 

Topics :

EUROoC 2019 Conference covers all aspects related to the research, development and application of Organ-on-Chips. Scientists and developers are invited to submit their original contributions in one or more of the following topics:

• Micro- and Nanoengineering
• Microfluidic interfacing
• Actuators for dynamic culture environments
• Integrated sensors
• Cellular engineering
• 3D cell culture environments
• Scaling
• Automation
• User-friendliness

We are looking forward to meeting you Graz! REGISTRATION

 

ORCHID Questionnaire on training needs of the next generation OoC reseachers and technicians

Within the ORCHID project, the main goal is to create a roadmap for organ-on-chip technology and to build a network of all relevant stakeholders in this promising innovative field.

By identifying you as a stakeholder, we would like to draw your attention concerning the training needs of the next generation of researchers and technicians in the Organ-on-a-chip field. We invite you to give us your opinion on this by answering this 15 minute questionnaire.

Feel free to disseminate this questionnaire within your network of interested researchers in universities, research institutes, industries, hospitals and regulatory bodies so that they could share their views too. We thank you very much for your contribution.

European Organ-On-Chip Society launched

PRESS RELEASE, 13 November 2018

The new European Organ-on-Chip Society (EUROoCS) was officially launched at the third International Organ-on-Chip Symposium, held on 8 and 9 November 2018 at the University of Technology in Eindhoven, the Netherlands. The Society will encourage development and coordination of Organ-on-Chip research in Europe in support of better health for all. Membership will be open from 2019 to all researchers in the field, providing access benefits to the pending digital Organ-on-Chip platform, the annual meeting and the future society journal.

In the presence of 180 scientists from twelve countries Christine Mummery, chair of the new Society, initiated the launch ceremony, which subtly referred to the annual light festival in Eindhoven, site of the launch, and the classical light bulb developed there a century ago. “It is a European Society but everyone worldwide is welcome to join. We are just at the early start, and there is much work to be done before we are operational and everybody can sign in. But we look forward to being the forum for this research in Europe and we are here to stay,” Janny van den Eijnden-van Raaij of hDMT says, among the first Board members of EUROoCS.

Accelerating Organ-on-Chip research
The purpose of the Society is to encourage and develop Organ-on-Chip research, and to provide opportunities to share and advance knowledge and expertise in this field towards a better health for all. EUROoCS is one of the first outcomes of the Horizon 2020 project ORCHID (Organ-on-Chip In Development), that aims to create a roadmap for Organ-on-Chip technology and to build a network of all parties involved.

Open for all researchers
Membership is open from 2019 to all researchers worldwide in the Organ-on-Chip field. The annual European Organ-on-Chip symposium will be organized in a different country in Europe each year. The next will be held in Graz, in Austria, on 2 and 3 July 2019. It will provide many opportunities for scientific discussion and interaction, and bring together young scientists with top experts in the field.

Easy connection via platform and journal
The membership will have many advantages for scientists, in particular finding collaborators via the digital Organ-on-Chip platform presently under construction, and disseminating results via the future Society journal.

The first Board members
The first Board of EUROoCS has the following members:

ORCHID interim roadmap report proudly presented

The ORCHID team was proud to present the first interim roadmap report entitled: ‘Organ-on-Chip in Development: Towards a European roadmap for Organ-on-Chip’ during the International Organ-on-Chip Symposium on November 8-9 2018 in Eindhoven, the Netherlands.

This report surveys the current landscape in the research, development, applications and market opportunities for Organ-on-Chip devices to establish the pillars of a European OoC ecosystem. Based on a bibliometric study, a market analysis, expert interviews, and panel discussions held at the ORCHID Vision Workshop (Stuttgart, 23 May 2018), this report outlines presently unmet needs, key challenges, barriers and perspectives of the field, and finally proposes recommendations towards the definition of a European roadmap that could render OoC systems (OoCs) realistic models of human (patho)physiology in the near future.

For the report click here.

Soheila Zeinali wins Best Poster Award IOOCS18

Soheila Zeinali from the Organs-on-Chip technologies group of the University of Bern (Switzerland) received the Best Poster Award at the International Organ-on-Chip Symposium 2018 (IOOCS 2018) in Eindhoven, the Netherlands. This year there were no less than 55 poster presentations which were all of high quality according to the scientific jury.

The poster jury, consisting of professors Ronald Dekker (chair; TUDelft, Netherlands), Cecilia Sahlgren (Åbo Akademi University, Finland), Shuichi Takayama (Georgia Tech, USA), and Jaap den Toonder(TU/e, Netherlands), had a hard time selecting the poster award winner from the high-quality poster contributions. First, 20 candidates were selected based on the submitted abstract, according to the rating by the scientific program committee. These posters were visited by the poster jury, and evaluated on the basis of four criteria: poster layout, presentation, scientific quality and innovation.

The winner was Soheila Zeinali, with her poster “Role of Rhythmic Breathing Motions on In Vitro Pulmonary Vascular Remodeling”. Her poster had a clear and attractive layout, and she presented the poster clearly and with enthusiasm. The topic of the poster is a nice example of a novel technological development applied to a biologically relevant question, and shows the great advantage of organ-on-chip technology, since the results could not have been obtained with conventional approaches. A deserved winner!

Poster title: Role of Rhythmic Breathing Motions on In Vitro Pulmonary Vascular Remodeling
Soheila Zeinali1, Emily K. Thompson1, Thomas Geiser1, 2, 3 and Olivier T. Guenat1, 2, 4
1 Organs-on-Chip Technologies Laboratory, ARTORG Center, University of Bern, Bern, Switzerland
2 Department of Pulmonary Medicine, Inselspital, University Hospital of Bern, Bern, Switzerland
3 Department of Biomedical Research, University of Bern, Bern, Switzerland
4 Division of General Thoracic Surgery, Inselspital, University Hospital of Bern, Bern, Switzerland

You can download her poster abstract here.

An Inserm Workshop on OoC gathered 70 people from Europe, in Bordeaux

An Inserm workshop dedicated to Organ-on-Chip (OoC) and entitled “OoC : understanding and mimicking living organisms for better treatment”, was organized in October 2018, in France.

This high-level training session, consisting of both theoretical and practical phases, aimed to educate, transfer knowledge and experiences to a public having a direct interest in OoC.

Around 70 people from Europe and the USA were present, including scientists, researchers, technicians and medical doctors working in academic government-funded bodies, teaching hospitals and companies in health-related industries.

Learn more