New publication on designing microphysiological systems for cardiac modelling

Researchers from the Centre of Excellence in Body-on Chip Research at Tampere University (Finland) have published a review regarding designing  microphysiological systems for cardiac modelling. The review is titled ‘Building blocks of microphysiological system to model physiology and pathophysiology of human heart’.

The centre focuses on modelling of hypoxia in cardiac ischemia, brain stroke and obesity related conditions. Developing chip platforms and monitoring technologies for controlling and monitoring oxygen as well as hydrogel development are also the core actions of the centre.

Link to centre’s website.

Report of the European Medicines Agency 3Rs Working Party (3RsWP) public stakeholder session on the 2023 work plan

On 28 February 2023, the newly established EMA Joint CHMP/CVMP 3Rs Working Party (3RsWP) hosted a virtual public session that was broadcast and open to all stakeholders. The aim of this public session was to present the 3RsWP work plan and priorities for 2023. In addition, an opportunity was provided to stakeholders to comment and provide their views on the working party’s activities. This report provides a summary of the topics discussed during the public session, including the input received from the stakeholders during the interactive SLIDO session.

Download the report here.

SensOoChip CRACK IT Challenge

NC3Rs has recently announced their 2023 CRACK IT Challenges which includes a mega-Challenge focused on organ chip technology development with £2.6M of funding available to European researchers.

This Challenge aims to improve the utility and reproducibility of connected organ-on-a-chip (OoC) devices by integrating real-time multiparametric monitoring.

For more information on how to apply, register for the SensOoChip launch webinar on Tuesday 5 September 2023, 14:00 – 15:15 (BST)

Further guidance will be made available following the launch webinar.

To find out more about the Challenge aims and deliverables read the Challenge brief.